产品货号：
GS4644
中文名称：
重组小鼠CT-1
英文名称：
Recombinant Murine Cardiotrophin1
产品规格：
2μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 21.5kDa,a single non-glycosylated polypeptide chain containing 203 amino acids.
储存条件：冷冻（-20℃）
概述
Cardiotrophin-1(CT-1)is a member of the cytokine family which also includes IL-6,IL-11,leukemia inhibitory factor(LIF),oncostatin M(OSM),and ciliary neurotrophic factor(CNTF).CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart,skeletal muscle,ovary,colon,prostate and fetal lung.In addition,CT-1 which induces cardiac myocyte hypertrophy in vitro can bind to and activate the ILST/gp130 receptor.Murine CT-1 encodes a 203 amino acid(a.a.)residue protein that lacks a hydrophobic signal peptide.Human and murine CT-1 share 80%a.a.sequence identity and exhibit cross-species activity.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组小鼠CT-1，CT-1, Murine，Recombinant Murine Cardiotrophin1
储存条件：冷冻（-20℃）
概述
Cardiotrophin-1(CT-1)is a member of the cytokine family which also includes IL-6,IL-11,leukemia inhibitory factor(LIF),oncostatin M(OSM),and ciliary neurotrophic factor(CNTF).CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart,skeletal muscle,ovary,colon,prostate and fetal lung.In addition,CT-1 which induces cardiac myocyte hypertrophy in vitro can bind to and activate the ILST/gp130 receptor.Murine CT-1 encodes a 203 amino acid(a.a.)residue protein that lacks a hydrophobic signal peptide.Human and murine CT-1 share 80%a.a.sequence identity and exhibit cross-species activity.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞95%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.5ng/ml,corresponding to a specific activity of>2.0×106 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMTris,300 mM NaCl,pH 8.5. |
| 内毒素 | Less than 1 EU/μg of rMuCT-1 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | MSQREGSLED HQTDSSISFL PHLEAKIRQT HNLARLLTKY AEQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSVLPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP GPEPVTVATL FTANSTAGIF SAKVLGFHVC GLYGEWVSRT EGDLGQLVPG GVA |
相关搜索：重组小鼠CT-1，CT-1, Murine，Recombinant Murine Cardiotrophin1